Date: {{$ActivityAssignDate}}

Dear Dr. {{$doctorName}},

Subject: Participation in survey “Usage of antioxidants in routine clinical practice”

The human eye is subjected constantly to oxidative stress due to daily exposure to sunlight, high metabolic activities, and oxygen tension. Reactive oxygen species generated from environmental insults and pathological conditions render the human eye particularly vulnerable to oxidative damage. The ocular surface composed of the tear film, the cornea, and the aqueous humor forms the first physical and biochemical barrier of the eye and plays a pivotal role in combating free radicals. These ocular compartments are enriched in certain antioxidants in the form of metabolic enzymes or small molecules. Such an antioxidant defense system in the ocular surface is essential for the maintenance of redox homeostasis in the eye and protection against oxidative damage.

Anthocyanins and vitamins play a role in the treatment and prevention of various ophthalmic diseases.

There is limited real-world data available on the usage of antioxidants in asthenopia, accommodation insufficiency and diabetic retinopathy management in India.

This multicentric survey is designed to understand the usage of antioxidants in asthenopia, accommodation insufficiency and diabetic retinopathy management in India If you agree to participate, you will be required to respond to questions of the enclosed questionnaire. We trust you and we are partners in promoting safe and effective drug therapy. In that spirit we hope you will consent to participate in this survey. If you do, please sign and return the enclosed reply along with your visiting card for accuracy of records.