Subject: Assessment of Prevalence, Diagnostic and Treatment Approach Towards the Usage of Probiotics in Pre and Post-Surgical Patients in India (PREDICT-PRO)
The human gut microbiota has gained increasing recognition for its role in influencing surgical outcomes, including post-operative recovery, infection rates, immune modulation, and overall patient well-being. Imbalances in the gut microbiota (dysbiosis) have been linked to increased post-surgical complications and delayed healing, particularly in high-risk and immunocompromised patients.
Each year, approximately 234 million surgical operations are performed worldwide. There are an estimated 30 million surgical procedures carried out in India every year. The majority of surgical patients recover without experiencing POCs (post-operative complications). However, a significant number do experience surgical site infection, urinary tract infection, pneumonia, and sepsis. These complications result in increased use of antibiotics, length of hospital stay, cost, and mortality. Prevention of POCs is therefore a major challenge. Proper regimen, dose, time, and duration of antibiotic prophylaxis administration are considered to be a standard to prevent POCs.
Probiotics confer health benefits when administered in adequate amounts and have emerged as a potential adjunct to surgical care. However, despite promising evidence, clinical adoption and standardization of probiotic use across surgical specialties remain highly variable due to a lack of consensus, differing perceptions among clinicians, and limited real-world data in Indian patients.
This survey aims to assess the awareness, prevalence, clinical rationale, diagnostic evaluation, and prescription practices of probiotics among healthcare professionals managing surgical patients in India. It also seeks to understand perceived benefits, limitations, and barriers to implementation in real-world settings. The findings will help guide future research, support the development of evidence-based guidelines, and enhance multidisciplinary strategies for optimizing surgical outcomes through microbiota modulation.
If you agree to participate, you will be required to respond to the questions of the enclosed questionnaire. We trust you, and we are partners in promoting safe and effective drug therapy. In that spirit, we hope you will consent to participate in this study. If you do, please sign and return the enclosed reply along with your visiting card for accuracy of records.
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