Subject : A real-world survey to understand the perception of Dyslipidaemia, hypertriglyceridemia and Diabetes association and management in Indian population with high risk of cardiovascular disease (RED)
Diabetes mellitus (DM) is a metabolic disorder that frequently predisposes to cardiovascular diseases (CVD), making CVD one of the leading causes of morbidity and mortality in both type 1 and type 2 diabetes mellitus patients (T1DM and T2DM). Good glycaemic control in T1DM leads to fewer cardiovascular events. However, the presence of CVD in T2DM patients is independent of intensive glycaemic control. Aside from insulin resistance and deficiency, serum lipid abnormalities, also known as dyslipidaemia, are common in T2DM patients, a condition known as metabolic syndrome.
Diabetes-related dyslipidaemia is defined by a decrease in high density lipoprotein (HDL) cholesterol, an increase in triglyceride levels, and a mild effect on low-density lipoprotein (LDL) cholesterol. The pathogenesis of dyslipidaemia involves the liver producing too many very low-density lipoproteins (VLDL), which contributes to an increase in serum triglyceride levels. As a result of the dysregulation of triglyceride and serum cholesterol levels, diabetic dyslipidaemia is associated with atherosclerotic cardiovascular disease (ASCVD),
Dyslipidaemia is a major modifiable risk factor for type 2 diabetes, atherosclerosis, stroke, and cardiovascular disease. However, increased urbanisation, socioeconomic development, and lifestyle changes have increased the risk of dyslipidaemia in recent years.
The first-line approach in the management of dyslipidaemia in diabetes is frequently lifestyle changes emphasising weight loss, dietary changes, and regular physical aerobic exercise. Because obesity is associated with insulin resistance and increased lipid levels, weight loss can significantly improve lipid levels and reduce cardiovascular risk factors. Pharmacological treatment approaches for diabetic dyslipidaemia include both glucose and lipid lowering drugs. Some diabetes glycaemic control agents have been shown to influence lipid levels as well as glucose metabolism.
The purpose of this survey is to understand the perception of Dyslipidaemia, hypertriglyceridemia and Diabetes association and management in Indian population with high risk of cardiovascular disease and also help to address the current need gaps to look at potential interventions at patient level.
If you agree to participate, you will need to provide assessment response, on to the standard questionnaire form. A link will be provided for the same on your registered email address.
We trust you and we are partners in safe and effective drug therapy. In that spirit we hope you will consent to participate in this survey.
If you agree to participate in the said study, we would request you to sign and return the enclosed reply along with your visiting card for accuracy of records.
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