Date: {{$ActivityAssignDate}}

Dear Dr. {{$doctorName}},

Subject: A survey among dermatologists to understand acne prevalence and its management in Indian patients

Acne is one of the most common skin diseases seen in clinical practice and is caused by multiple factors which originates in the pilosebaceous follicle. The four major factors contributing to acne development are sebum hyper secretion (often alongside qualitative and quantitative alterations in sebum composition), abnormal keratinocyte proliferation and differentiation in hair follicles, overgrowth of skin micro flora Cutibacterium acnes (C. acnes), and host inflammatory response.

Topical therapy is sufficient for mild cases. A combination of topical and systemic drugs is usually preferred in moderate cases and also in severe cases (nodulocystic acne) where oral isotretinoin option can also be considered. Other options for female patients of severe nodulocystic acne are oral antibiotics and anti-androgens.

This survey has been undertaken among dermatologists to understand acne vulgaris prevalence and its management in Indian patients.

As you will be spending some extra time to give your feedback on the questionnaire based on your clinical experience, we offer to pay you by cheque a professional fee of Rs {{$contractAmount}}, on receiving the completed Survey Questionnaire Form from you.

We trust you and we are partners in promoting safe and effective drug therapy. In that spirit we hope you will consent to participate in this study. If you do, please sign and return the enclosed reply along with your visiting card for accuracy of records.