Date: {{$ActivityAssignDate}}

Dear Dr. {{$doctorName}},

Subject: An epidemiological survey among Dermatologist evaluating diagnosis and management of acne vulgaris in Indian population

Acne is one of the most common skin diseases seen in clinical practice and is caused by multiple factors which originates in the pilosebaceous follicle. The four major factors contributing to acne development are sebum hyper secretion (often alongside qualitative and quantitative alterations in sebum composition), abnormal keratinocyte proliferation and differentiation in hair follicles, overgrowth of skin micro flora Cutibacterium acnes (C. acnes), and host inflammatory response.

Topical therapy is sufficient for mild cases. A combination of topical and systemic drugs is usually preferred in moderate cases and also in severe cases (nodulocystic acne) where oral isotretinoin option can also be considered. Other options for female patients of severe nodulocystic acne are oral antibiotics and anti-androgens.

Although a number of studies have been carried out on acne, large-scale population studies which can really help to explicate the epidemiology and pathogenesis of acne have been limited and almost exclusively conducted in Western countries.

This survey has been undertaken to assess the epidemiological characteristics and treatment patterns of Acne Vulgaris management in Indian patients.’

We trust you and we are partners in promoting safe and effective drug therapy. In that spirit we hope you will consent to participate in this study. If you do, please sign and return the enclosed reply along with your visiting card for accuracy of records.