Date: {{$ActivityAssignDate}}

Dear Dr. {{$doctorName}},

Subject: : Understanding the in-clinic usage of tofacitinib in real life scenario

Tofacitinib, an immunomodulator of Janus kinase inhibitor (Jakinib) family, blocks tyrosine kinases of the Janus family. Janus kinase-signal transducer and activator of transcription (JAK/STAT) is an intracellular pathway that drives downstream signaling of several pro-inflammatory pathways. The efficacy and safety of Jakinibs is well-established in inflammatory disorders.

We invite you to participate in this survey. All you need to do is to report on a standard survey questionnaire your experience with tofacitinib in auto-immune conditions. Thus, we are seeking your feedback of your clinical experience in managing autoimmune conditions.

If you agree to participate, you will be needed to complete a survey questionnaire. A monitor will be available to assist you in verifying and collecting the survey questionnaire.

We trust you and we are partners in promoting safe and effective drug therapy. In that spirit we hope you will consent to participate in this study.