Date: {{$ActivityAssignDate}}

Dear Dr. {{ $doctorName }},

Subject: Participation in survey "Research and Vision on antibiotics usage pattern & awareness of antibiotic resistance (SAVE AB study)"

Bacterial infections have been, and are very likely to continue to be, among the most serious problems in medicine. One of the main reasons for this is that a significant proportion of these infections are endogenous, and the etiologic agents originate from the human bacterial flora.

Antibiotics are common agents used in modern healthcare. Antibiotics are compounds that target bacteria and, thus, are intended to treat and prevent bacterial infections.

Despite the great expansion of antibacterial in the 1960s and 1970s, as documented by the development of a range of new products and their introduction into practice, bacterial infections remain a major issue of increasing importance. Modern medicine is even confronted with the real threat that antibiotics may lose.

The use of antibacterial agents is essential in the treatment of patients with bacterial infections. However, the effectiveness of antibiotics is increasingly limited by the growing resistance of pathogenic bacteria, which significantly increases the likelihood of failure of antibiotic therapy.

Respiratory tract infections (RTIs) are any infection of the sinuses, throat, airways or lungs. Healthcare professionals generally make a distinction between: upper respiratory tract infections- which affect the nose, sinuses and throat and lower respiratory tract infections which affect the airways and lungs. Upper respiratory tract infections (URTIs) include pharyngitis/tonsillitis, sinusitis, rhinitis, rhino-sinusitis and otitis media. Lower respiratory tract infections (LRTIs) include acute bronchitis, bronchiolitis, pneumonia and tracheitis.

Antibiotics are often indicated for the management of various upper respiratory tract infections, including acute otitis media, sinusitis, tonsillitis, pharyngitis and lower respiratory tract infection like community acquired pneumonia etc.

This cross-sectional study is designed to understand the epidemiology, etiology and antibiotics usage pattern & awareness of antibiotic resistance in India.

If you agree to participate, you will be required to respond to questions of the enclosed questionnaire. We trust you and we are partners in promoting safe and effective drug therapy. In that spirit we hope you will consent to participate in this survey. If you do.

please sign and return the enclosed reply along with your visiting card for accuracy of records.