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Male Female
Type of practice
Private clinic
Private hospital
Private hospital with medical college
Government hospital
Government hospital with medical college
Metros
Tier 1 city
Tier 2 city
Rural Market
Dual Energy X- ray Absorptiometry (DEXA)
X-ray
Magnetic Resonance Imaging (MRI) scan
Computed Tomography (CT) scan
Any other
< 5
5-10
11-20
>20
<50 years
50-60 years
60-75 years
>75 years
Vertebrae > distal radius > femoral neck
Femoral neck > vertebrae > distal radius
Distal radius > vertebrae > femoral neck
Vertebrae > femoral neck > distal radius
Femoral neck > distal radius > vertebrae
Distal radius > femoral neck > vertebrae
Low back pain
Tibial shin pain
Generalized weakness and fatigue
Rib pain
Incidental finding in patients with fracture
Incidental finding in patients with pain
Incidental finding in patients with general fatigue
Referred by other specialties
Pain
Leg cramps
Bone pain
Functional impairment
Porous, weak, brittle bones without fragility fractures
Porous, weak, brittle bones with fragility fractures
21-30
>30
<5%
5-20%
21-30%
>30%
Postmenopausal
Steroid induced
Medication induced other than steroid
Other cause
T score ≤ -2.5
T score ≤ -2.5 with fragility fractures
Severe symptoms like pain and loss of height
Assessment of serum parathyroid levels
Assessment of serum calcium levels
Assessment of serum vitamin D levels
Assessment for malignancy
Assessment for metabolic bone disorders
Initiate teriparatide without any laboratory investigations as no major tolerability issues seen in my clinical practice
Pain reduction
Radiological improvement
Functional improvement
Prevention of recurrent fractures
Other
<10%
11-20%
All patients
<3 months
3-6 months
6-12 months
12-18 months
18-24 months
Denosumab is preferred as it is not associated with hypercalcemia
Bisphosphonates are preferred as they are not associated with hypercalcemia
Teriparatide is preferred as it doesn’t cause significant hypercalcemia
Yes
No
Mild
Moderate
Severe
Denosumab first followed by teriparatide
Teriparatide first followed by denosumab
Teriparatide and denosumab simultaneously followed by teriparatide alone
Teriparatide and denosumab simultaneously followed by denosumab alone
Cancellous bone responds better to teriparatide
Cortical bone responds better to teriparatide
Cancellous and cortical bones respond to teriparatide equally
Diaphyseal bone responds better to teriparatide
Metaphyseal bone responds better to teriparatide
Diaphyseal and metaphyseal bones respond to teriparatide equally
Invasive route of administration
Cost of drug
Daily administration of drug
Lack of patient awareness
Poor patient compliance
Increase in bone mineral density on DEXA scan
Increase in bone formation markers e.g. P1NP
Increase in bone formation marker P1NP
Increase in BMD in DEXA scan
Strongly agree
Agree
Neutral
Disagree
Strongly disagree