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Evaluation of Efficacy & Safety of Rosuvastatin in Indian Dyslipidemia Patients

  1. Asian Indians have a unique pattern of dyslipidaemia characterized by? *

  2. South Asians manifest CVD at lower levels of total cholesterol compared with other ethnic groups? *

  3. Asian Indians have been found to develop cardiovascular diseases at a younger age than other populations? *

  4. Is there any difference in your experience with different classes of antidiabetic drugs with respect to advantage and disadvantage? *

  5. Do you agree that some drug classes like gliptins address more defects of T2DM pathogenesis than others? *

  6. How much presence of CVOT trials data is important in selecting gliptins? *

  7. Do you perceive all gliptins are same in terms of efficacy and safety? *

  8. Which is not seen in T2DM? *

  9. Which component is absent in Ominous Octet causing hyperglycemia? *

  10. Which of the following are Incretin hormones? *

  11. India ranks number _____ in the people living with type 2 diabetes Mellitus *

  12. Increased risk of HHF is seen in following DPP4i CVOT- *

  13. As per the Ominous octet of T2DM, Hyperglycaemia results due to _____________ by the kidneys. *

  14. Rosuvastatin belongs to the following class of drugs ______________________ *

  15. Which of the following medication when prescribed with rosuvastatin for the treatment of hyperlipidaemia may increase the patient's risk of developing rhabdomyolysis? *

  16. Which statement below accurately describes how rosuvastatin works to lower cholesterol levels? *

  17. Which of the following findings below demonstrate that rosuvastatin is providing therapeutic effects to this patient? Select-all-that-apply *

  18. You're providing education to a group of participants in the community about cholesterol and cardiac disease. Which statements below verbalized by some of the participants are inaccurate and require you to provide clarification? *

  19. A patient has been taking Rosuvastatin and reports to you that they are experiencing soreness and weakness of the muscles. What lab investigation will you suggest immediately? *

  20. Which food item below should the patients avoid including in the food plan while taking rosuvastatin? *

  21. Your patient who is taking rosuvastatin develops yellowing of the skin, abdominal pain in the right upper quadrant, and nausea. What lab result below correlates with this finding? *

  22. Rosuvastatin are typically effective when combined with resins, niacin, or ezetimibe in decreasing LDL serum levels. *

  23. Based on patterns of metabolism by hepatic microsomal metabolizing systems, pravastatin and rosuvastatin appear to be statins of choice for use with which one(s) of the following medications? (Select-all-that-apply) *

  24. Inactive lactone prodrug(s) in the statin category: (Select-all-that-apply) *

  25. Most of the statins are absorbed following oral administration in the range of 40%-75%. This statin, however, is almost entirely absorbed. *

  26. Rosuvastatin should be used cautiously and with decreased doses in patients exhibiting hepatic disease, elderly patients, and north Asians. *

  27. Satins, with some exceptions, should be given in the evening because cholesterol synthesis mainly occurs in the evening. *

  28. Rosuvastatin exhibit high first-pass hepatic metabolism. *

  29. Guidelines for statin use in children are same as for adults. *

  30. Choose the correct statement(s) concerning rosuvastatin: *

  31. In pregnant women or women likely to become pregnant and exhibit hyperlipidaemia reductase inhibitors (statins) are the agents of choice for lipid lowering effect. *

  32. Either statins or bile-acid sequestrants are considered first-line agents due to comparable efficacy. *

  33. This statin has been approved for children eight years or older for use in the presence of heterozygous familial hypercholesterolemia. *

  34. Choose the correct statement(s) concerning combination of gemfibrozil with a statin. *

  35. Regarding drug combinations, which one(s) of the following is/are correct? *

  36. Statins used in combination with bile acid-binding resins decrease LDL-C by 20%-30% compared to statins alone. *

  37. Administration of niacin in combination with a reductase inhibitor (statin) or a resin-type agent usually results in normal LDL levels in patients with heterozygous familial hypercholesterolemia. *

  38. Which one of the following represents the major statin-associated adverse effect? *

  39. The likelihood of rhabdomyolysis following statin administration is not correlated with either dose or plasma concentration. *

  40. Which one(s) of the following statements is/are correct? *

  41. For coronary heart disease age >45 years in men and >55 years in women represent a risk factor. *

  42. Choose the correct statement(s) regarding coronary heart disease in the type II diabetic patient. *

  43. LDL-cholesterol baseline levels correlate with long-term cardiovascular risk. *

  44. Risk factor(s) associated with coronary heart disease: (Select-all-that-apply) *

  45. Which one(s) of the following disorders represent secondary causes of dyslipidemia with the major effect on cholesterol vs. triglyceride levels? *

  46. Which one(s) of the following statements is/are true? *

  47. Administration of rosuvastatin results in reduced total and vascular disease mortality in the diabetic patient due to prevention of cardiovascular disease events. *

  48. Pleiotropic effects of statin, apart from cholesterol-lowering actions, include; *

  49. Which of the following statins, according to you, has a higher capacity for lowering LDL-cholesterol? *

  50. Disparity in cardiovascular outcomes exists by race/ethnicity and gender. *

  51. Do you think that statin therapy is underused? *

  52. Adherence to medication is inversely related to the number of pills and the number of doses per day. *

  53. Combination therapy reduces the risk of CV events. *

  54. Coronary heart disease and stroke are the top two causes of death globally. *

  55. Statins have beneficial effects on the cerebral circulation during ischemic stroke. *

  56. Longer duration of statin use can lower the risk of intracerebral hemorrhage. *

  57. Which of the following statements do you think is most related to Indian diabetic phenotype? (Tick any one) *

  58. As diabetes is a cardiovascular risk equivalent in general, do you believe diabetes increases the risk of Heart Failure manifold (Tick any one)? *

  59. How do you compare the risk of CKD as compared to Heart Failure in your diabetic patient population (Tick any one)? *

  60. Do you believe risk estimation with CV risk calculators & treatment recommendations by the guidelines are in consistency with the sound cost-benefit analysis? *

  61. What is preferred approach to treat dyslipidaemia in patient with ACS? (Sequential or Early Combination therapy) *
  62. What are the limiting factors for up titration of statins in practice? What is your preferred approach in such cases? *