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An observational cross-sectional survey study to understand the clinician approach to up dosing of anti-histaminic agents in management of allergic rhinitis(AR)
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Survey Questionnaire Form

  1. Which antihistamine do you most commonly prescribe for allergic rhinitis? *

  2. How often do you consider up-dosing antihistamines in your practice? *

  3. Which patient group do you most frequently up-dose for? *

  4. Which antihistamine do you prefer for up-dosing? *

  5. In your experience, which factor most influences your decision to up-dose an antihistamine? *

  6. What is the most common dose increment you use when up-dosing? *

  7. Have you observed significant clinical improvement with up-dosing? *

  8. Do you consider up-dosing to be a safe practice in allergic rhinitis? *

  9. What is your primary concern with up-dosing antihistamines? *

  10. Do you believe the current guidelines support up-dosing of antihistamines in allergic rhinitis? *

  11. Which symptom do you find most resistant to standard antihistamine dosing? *

  12. Have you encountered patients requiring more than twice the standard dose of an antihistamine? *

  13. Which patient profile do you think benefits most from up-dosing? *

  14. How do you monitor patients for adverse effects when up-dosing? *

  15. Do you educate patients on potential risks of up-dosing? *

  16. Usually for how long are patients continued on higher doses? *

  17. Once higher doses are not required, are patients tapered down to same molecules preferably? *

  18. Are corticosteroids definitely given in patients where higher doses of anti-histamines are used? *

  19. How much percentage of AR patients respond to higher doses of anti-histamines? *

  20. Alertness is least affected by which anti-histamine? *

  21. In which clinical scenarios do you consider up-dosing to be most appropriate? *
  22. Have you observed differences in response among different antihistamines when up-dosing? *
  23. How do you balance efficacy and safety while considering up-dosing? *
  24. Have you encountered patients with side effects related to up-dosing? If yes, what were they?
  25. What additional evidence or guidelines would help you make better decisions on up-dosing antihistamines? *
  26. How do you counsel patients on the benefits and risks of up-dosing? *
  27. What is your opinion on the cost-effectiveness of up-dosing antihistamines compared to alternative treatments? *
  28. Have you seen any difference in up-dosing effectiveness in seasonal vs. perennial allergic rhinitis? *
  29. Do you believe that more research is needed on the long-term safety of antihistamine up- dosing? Why? *
  30. How do you approach antihistamine up-dosing in patients with multiple comorbid allergic conditions? *