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≤10%
11-20%
21-30%
>30%
0-10 year
11-20 year
21-30 year
30-40 year
>40 year
Menstrual irregularity
Hyperandrogenism
Hirsutism
Alopecia
Other
Clinical symptoms
Rotterdam Criteria
National Institute of Health (NIH) Criteria
Yes
No
Risk of future infertility
Risk of Type 2 diabetes mellitus
Risk of Metabolic syndrome
Risk of Cardiovascular disease
Lifestyle modification
Nutritional supplement
Drug therapy
Clomiphene citrate (CC) with or without Metformin
Letrozole with or without Metformin
Metformin without ovulation inducing agents
Gonadotropins with or without Metformin
Polycystic ovary syndrome (PCOS) women
Clomiphene citrate (CC) resistant
For intrauterine insemination
IVF/ICSI
2.5 mg/day
5 mg/day
7.5 mg/day
10 mg/day
5 days
7 days
10 days
14 days
It does not deplete ERs throughout the body
It keeps the hypothalamic-pituitary axis intact
It is short acting (45 min half‑life)
Excellent
Very Good
Good
Fair
Poor
Effectiveness
Tolerability
Patient compliance
Reliability
All of the above