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A survey among dermatologist to understand usage pattern of Levocetirizine updosing in chronic spontaneous urticaria (CSU) in India

Survey Questionnaire Form

Doctor’s details

Age *

Gender *

Male Female

Doctor’s Degree *

Years of clinical practice *

< 5 years

5-10 years

11-20 years

>20 years

Predominant type of practice *

Multi-specialty hospital

Clinic/ nursing home

Government hospital/ medical college

Mixed

Specialty *

Place of practice *

Tier 1 city

Tier 2 city

Tier 3 city

Rural area

Questionnaire

What percentage of your CSU patients, do you need to up dose the second generation anti histamine? *

up to 25%

25-50%

50-75%

75-100%

According to you, which is the most effective second-generation antihistamine in terms of updosing for CSU? *

Levocetirizine

Fexofenadine

Desloratadine

Bilastine

Which factors makes second generation anti-histamines most effective and suitable for updosing in CSU? *

Long half life

less side effects

Better tolerated

Any other

Please Specify

After up dosing how long levocetirizine will take to show a favorable response? *

Updosing of Levocetirizine significantly impact on? *

Pruritus

Wheal number

Reducing angioedema

Any other

Please Specify

What percentage of refractory patients respond to up dosing of Levocetirizine? *

up to 20%

20-30%

30-50%

>50%

For evaluating efficacy of up dosing of Levocetirizine, which particular parameter do you consider? *

Does up dosing of second generation anti-histamines for insufficient response from the conventional dose results in dose-dependent increase adverse effects? *

If, answer to Q. 8 is yes, then which second generation anti-histaminic is least prone to have dose-dependent increase in adverse effects?

Levocetirizine

Fexofenadine

Desloratadine

Bilastine

What percentage of adult patients are unresponsive to the maximally up dosed Levocetirizine? *

up to 10%

10-20%

20-30%

30-40%

40-50%

How do you take care of cardiac monitoring while updosing of Levocetirizine in a refractory case of CSU? *

In CSU patient’s refractory to Levocetirizine up dosing, what is your next step? *

Add cyclosporine

Add Omalizumab

Start Omalizumab plus cyclosporine

For Pediatrics age group do you prefer updosing of levocetirizine & why? *

If, answer to Q. 13 is yes, then what percentage of pediatrics patients are unresponsive to the maximally up dosed levocetirizine?

up to 10%

10-20%

20-30%

30-40%

40-50%

What are your view on up dosing of levocetirizine in special populations like geriatric, pregnancy and lactation? *