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Male Female
Multi-specialty hospital
Clinic/ nursing home
Government hospital/ medical college
Mixed
High sodium intake
Physical inactivity
Family history
Inadequate sleep
Hyperaldosteronism
Ageing
<10%
10- 20%
20-30%
30-40%
40-50%
> 50%
Smoking
Lack of physical activity
Obesity
Diabetes
CKD
Heart Failure
Dyslipidemia
Coronary artery disease
10-20%
>30%
5-10%
11-20%
21-30%
31-40%
>40%
In <10% of the patients
10-25% of the patients
25-50% of the patients
>50% of the patients
Efficacy of the drug in reducing blood pressure
Lesser risk of hyperkalemia
Low fluid retention
Lesser risk of hypokalemia
Yes
No
<5
5-10
10-20
Any other
Uncontrolled hypertension on > 2 drugs
Uncontrolled hypertension to monitor nocturnal hypertension
Uncontrolled hypertension to monitor early morning surge
Blood pressure variability
<5%
>20%
Alpha blockers
Mineralocorticoid receptor antagonist
Non-steroidal mineralocorticoid receptor antagonist
Loop diuretics
Direct vasodilation agents like hydralazine
10% - 20%
21% - 30%
31% - 40%
Patients adhere to medicines better
Patients become watchful of their diet and exercise
Patients may get worried unnecessarily over wrong readings
It is risky as there is a tendency to lower dose/stop medicines without medical advice
Non-steroidal Mineralocorticoid Receptor antagonist without side effects like hyperkalemia
Direct renin inhibitors
RNA based therapies with prolonged action
Highly selective agents to target aldosterone