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Male Female
< 5 years
5-10 years
11-20 years
>20 years
Multi-specialty hospital
Clinic/ nursing home
Government hospital/ medical college
Mixed
Tier 1 city
Tier 2 city
Tier 3 city
Rural area
0-10
11-20
21-30
31-40
41-50
51-60
61-70
71-80
80-90
90-100
Minocycline
Doxycycline
Lymecycline
Any other
Highly lipophilic
Better penetration in the sebaceous gland
Can be taken with food
Less GI disturbances as compared to doxycycline
Minocycline 45/65 ER
Minocycline 100 mg OD
Minocycline 50 mg
Any other minocycline formulation
Once-daily dosing
Weight-based dosing
Can be taken with or without food
Within 1 week
1-2 weeks
2-3 weeks
3-4 weeks
A. Pregnancy
Yes
No
B. Lactation
Ozenoxacin
Clindamycin
Minimal systemic absorption and accumulation
Improves inflammatory and noninflammatory skin lesions
Once daily dosage: better compliance
Less resistance