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Post Operative Inflammation - Survey Questionnaire
  1. Surgical stress, pain and inflammation (IL-6, TNF-ɑ and IL-1) directly stimulate the HPA axis disrupting basal circadian patterns of cortisol secretion, with up to four-fold increase in cortisol levels and can be elevated for up to 7 days *

  2. Published data mentions, post-op inflammation is characterized by increased blood flow and vascular permeability, accumulation of leukocytes, and upregulation of inflammatory mediators. *

  3. Published data mentions, surgical inflammation is caused by inflammatory response related to surgery. Have you observed it in your clinical practice? *

  4. Possible factors modifying Surgical inflammation can be….. *

  5. Published data mentions, damage of the immune response could increase perioperative morbidity and mortality rates from infection in exposed patients. Have you observed this scenario in your clinical practice? *

  6. Published data mentions, both humoral and cellular immunity are dampened during surgical process and higher degree of surgical trauma determines greater immunodepression. Is this been observed in the clinical practice? *

  7. Published data mentions, post-surgery, wound healing is proceeded by hemostasis, inflammation, proliferation, and tissue remodeling. Is it clinically relevant as per your clinical experience? *

  8. What percentage of your OPD patients undergo a surgery or procedure? *

  9. Published data mentions surgical trauma may induce acute systemic inflammation which originally plays a role in immune defense from bacterial infection and in the wound healing process. Have you observed this in post operative patients? *

  10. Which are the 3 most common symptoms of post-op or peri-op inflammation you have observed in surgical patients? *

  11. Mostly for how many days you have observed, there is significant post-op/ procedure inflammation? *

  12. What percentage of post-op patients you have seen developing excessive inflammation? *

  13. What percentage of day care patients you have seen developing excessive inflammation? *

  14. What percentage of major surgical patients you have seen developing excessive inflammation? *

  15. In most of the cases, for how many days you prescribe anti-inflammatory drugs in minor post-op inflammation? *

  16. In most of the cases, for how many days you prescribe anti-inflammatory drugs in moderate post-op inflammation? *

  17. In most of the cases, for how many days you prescribe anti-inflammatory drugs in severe post-op inflammation? *

  18. Which are the 3 most common factors impacting surgical wound healing? *

  19. Do you feel nutritional status impacts surgical wound healing? *

  20. What dietary advice you commonly provide to your surgical patients? *

  21. Do you feel associated diabetes impacts surgical wound healing? What are the common precautions you take for diabetic patients when they undergo surgery? *

  22. Do you feel existing infection can impact surgical wound healing? What are the common precautions you take in those patients when they undergo surgery? *

  23. Which existing infections most commonly cause surgical wound infection as per your clinical experience? Bacterial, fungal, parasitic or any other? *

  24. Which bacterial infections most commonly cause surgical wound infection as per your clinical experience?
    Gm positive, Gm negative, anaerobic or mixed?     *

  25. Published data mentions, anti-inflammatory drugs can expedite surgical wound healing. Kindly opine based on your clinical experience. *

  26. Which are the common precautions you take to control excessive post-op inflammation in your patients? *

  27. As per published data, higher CRP levels (>150 mg) on postoperative days 3–5 appear to reflect an exaggerated inflammation associated with increased risk of complications and worse outcomes. *

  28. In your clinical Practice, in which surgery or procedures you frequently prescribe anti-inflammatory drugs? *

  29. In your clinical Practice, in which surgery or procedures you frequently prescribe Trypsin Bromelain Rutoside combination? *

  30. In your clinical Practice, for which purpose you mostly prescribe TBR formulations? *