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An observational cross-sectional survey study to understand the treatment pattern of Chronic Mucus Hypersecretion (CMH) and the potential role of Acebrophylline + N- Acetylcysteine in the management of mucus hypersecretion.

SURVEY QUESTIONNAIRE
  1. What is the prevalence of Mucus hypersecretion patients in your practice? *
    2. %
    		To
    %
    {{--
    % to %
    --}}
    {{--
    --}}
  2. What are the most common symptoms that patients with chronic mucus hypersecretion present in your practice? *
    3. Symptoms Tick all applicable
    Sneezing

    Tearing

    Sputum production

    Breathlessness

    Mention if any other

    {{--

    --}}
  3. What are the most common signs you observe in your chronic mucus hypersecretion patients? *
    4. {{-- --}}
    Signs Tick all applicable
    Post Nasal Drip

    Rhinorrhea

    Nasal Congestion

    Ocular redness & secretion

    Mention if any other

    Mention if any other

    {{--

    --}}
  4. What are the diagnostic tests used in your patients presenting with Chronic Mucus Hypersecretion? *
    5. {{-- --}}
    Test Tick all applicable
    Bronchoscopy

    Ultrasound

    HRCT

    Sputum culture & Sensitivity

    Mention if any other

    Mention if any other

    {{--

    --}}
  5. What are the most common causes of Chronic Mucus Hypersecretion? *
    6. {{-- --}}
    Causes Tick all applicable
    COPD

    Asthma

    Non-Cystic Fibrosis Bronchiectasis

    Respiratory Tract Infections

    Mention if any other

    Mention if any other

    {{--

    --}}
  6. What are the most common co-morbidities observed in Chronic Mucus Hypersecretion patients in your practice? *
  7. What is your first line treatment of choice in Chronic Mucus Hypersecretion patients in your practice? *
    8. Drug Class Dosage Form
    (Tablet/Inhaler)    		 Dose Duration of therapy
    Corticosteroids

    Methylxanthines

    Alpha blockers

    Mucolytics

    Anti-histaminic

  8. How long do you follow up with your Chronic Mucus Hypersecretion patients? *

  9. How do you treat a severe mucus hypersecretion patient? *
  10. In your practice, do your Chronic Mucus Hypersecretion patient require supportive care? *

  11. What is the relative % patients of Chronic Mucus Hypersecretion you treat with the below formulations? *
    12. Oral tablet
    %
    Inhalation
    %
    Both
    %
  12. Do you use combination therapy of Acebrophylline + N-Acetylcysteine in your Chronic Mucus Hypersecretion patients? *

  13. If yes, Mention the medical rationale
    14. {{-- --}}
  14. What is the duration of treatment of Acebrophylline + N-Acetylcysteine combination in your Chronic Mucus Hypersecretion patients in your practice? *

  15. In what type of patients do you prefer Acebrophylline + N-Acetylcysteine combination: *
    16. {{-- --}}
    Indication Tick all applicable
    COPD

    Asthma

    Bronchiectasis

    Chronic Bronchitis

    Mention if any other

    Mention if any other

    {{--

    --}}
  16. Do you shift your patients from Acebrophylline + N-Acetylcysteine to plain Acebrophylline after a few days? *

  17. Which add-on therapies do you prescribe for symptomatic relief in your Chronic Mucus Hypersecretion patients? *
    18. {{-- --}}
    Formulation Tick all applicable
    Cough Syrup

    Nasal Decongestants

    Nebulization

    Antibiotics

    Mention if any other

    Mention if any other

    {{--

    --}}
  18. Which property of N-Acetylcysteine as per you is the most relevant that attributes to its efficacy? *
    19. {{-- --}}
    Properties Tick all applicable
    Mucolytic

    Anti-oxidant

    Anti-inflammatory

    Anti-biofilm

    Mention if any other

    Mention if any other

    {{--

    --}}
  19. What are the factors leading to the choice of therapy for Chronic Mucus Hypersecretion patients in your practice? *
    20. {{-- --}}
    PK/PD Properties Tick all applicable
    Rapid onset of action

    Symptom relief

    Duration of action

    Patient adherence

    Mention if any other

    Mention if any other

    {{--

    --}}
  20. Do you observe improved patient adherence with Acebrophylline + N-Acetylcysteine combination in fruit mixed flavour addressing palatability issues? *

  21. Elaborate on limiting factor/concerns of not using Acebrophylline + NAC for long term in chronic mucus hypersecretion. *
  22. What are the common side-effects you come across with use of plain N-acetylcysteine? *
  23. Does stepping down from Acebrophylline + N-Acetylcysteine combination to plain Acebrophylline benefits the chronic mucus hypersecretion patient? If yes, how? *

  24. Please elaborate the benefits/risks of using Acebrophylline + N-Acetylcysteine in Chronic Mucus Hypersecretion patients over plain Acebrophylline or plain N-Acetylcysteine. *
  25. Do you increase the dose of N-Acetylcysteine more than 1200mg per day? *

  26. Which medication do you prefer adding with Acebrophylline + N-Acetylcysteine combination in chronic mucus hypersecretion patients? *
    27. {{-- --}}
    Molecules Tick all applicable
    Montelukast

    Montelukast + Levocetrizine

    Montelukast + Fexofenadine

    Montelukast + Bilastine

    None

    Mention if any other

    Mention if any other

    {{--

    --}}
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