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<15
15-30
30-50
>50
Strongly agree
Agree
Neutral
Disagree
Strongly disagree
IBS-C
IBS-D
Mixed IBS
Unspecified IBS
By careful history and physical examination
Exclusion of other diseases
Laboratory examinations
Colonoscopy
Any other
Abdominal pain
Bloating
Constipation
Diarrhea
Complete blood count
Faecal occult blood
Stool microscopy and culture
Thyroid function tests
Erythrocyte sedimentation rate
C-reactive proteins
Yes
No
Manning Criteria
Rome IV
Rome III
<15%
15-30%
30-60%
60-90%
>90%
Anti-diarrheal such as loperamide
Rifaximin
5 HT3 antagonists such as ramosetron
Probiotics
Selective serotonin reuptake inhibitors
Anti-secretory such as racecadotril
Laxatives
Lubiprostone
Anti-depressants
7-10 days
15-20 days
up to 1-month
up to 3 months
Mention other duration, if any
400 mg TDS for 7 days
550 mg BD for 15 days
550 mg TDS for 15 days
400 mg BD for 15 days
Any other dose or duration
Patients with long standing disease
Patients having alarming features such as anaemia, rectal bleeding, and weight loss
Patients not responding to therapy
<10%
10-30%
30-50%
50-70%
>70%
10-20%
20-40%
40-60%
60-80%
>80%
Lack of specific laboratory tests and biomarkers
No specific and effective drug therapy available
Multifactorial aetiology
Lack of patient adherence to lifestyle modification and drug therapy