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Relevance of ARNi, Carvedilol, Ivabradine in Indian Heart Failure patients to Strengthen the Evidence based practice

  1. What are the signs of heart failure? *
  2. What are the common causes of heart failure? *
  3. What can be done to manage heart failure? *
  4. What are the four pillars of Heart Failure (HF)? *
  5. Do you prefer ARNI in HF with resistant hypertension? *
  6. Do you prefer ARNI in heart failure with preserved ejection fraction (HFpEF)? *
  7. Do you prefer ARNI in heart failure with mildly reduced ejection fraction (HFmrEF)? *
  8. What is your preferred method of therapy initiation in HF? *
  9. What is the most commonly used dose of ARNI *
  10. What is the limiting factor to up-titrate dose of ARNI *
  11. NT-proBNP is it preferred as first line screening tool in practice *
  12. Do you prefer ARNI in HF with renal impairment patients *
  13. What percentage of patients achieve the highest dose of ARNI *
  14. Lowering blood pressure significantly reduces cardiovascular morbidity and mortality. *
  15. The European Society of Hypertension/European Society of Cardiology guidelines recommend the use of β-blockers as first-line or second-line antihypertensive agents. *
  16. Which among the following is a 3rd generation β-blocker with additional alpha-blocking activity, used widely for the management of hypertension? *
  17. In contrast to classic β-blockers, carvedilol maintains cardiac output, has a lesser effect on heart rate, and decreases BP mainly by decreasing vascular resistance *
  18. Do you agree that Carvedilol decreases arterial BP to a greater extent than the traditional β-blocker in patients with moderate and essential hypertension? *
  19. β-blocker having vasodilatory properties, Carvedilol, has beneficial effects on glycemic control and insulin sensitivity *
  20. Carvedilol when given in hypertensive patients with type 2 diabetes leads to: *
  21. The risk for new-onset diabetes is lowered in patients receiving Carvedilol. *
  22. Do you agree α-blocking effect of Carvedilol may provide a superior benefit in terms of left-ventricular hypertrophy regression, compared with traditional β-blockers? *
  23. 6 months of daily therapy with Carvedilol 25 mg in elderly patients with essential hypertension and left-ventricular hypertrophy show *
  24. Do you agree Carvedilol exerts a renoprotective effect? *
  25. Addition of Carvedilol to conventional heart failure therapy in mild to moderate CKD patients is beneficial and safe. *
  26. The beneficial effect of carvedilol on kidney function is demonstrated by: *
  27. Do you agree Carvedilol has an excellent tolerability profile across a wide range of patient types, thus improving the potential for compliance? *
  28. Ivabradine is used to treat heart failure. How does it work? *
  29. What makes Ivabradine a good option to treat heart failure? *
  30. The European Society of Cardiology (ESC) recommends the use of ivabradine to- *
  31. The main effect of Ivabradine therapy is the substantial lowering of HR. *
  32. Recently updated HF guidelines recommend Ivabradine as a class II indication for reduction of HF hospitalizations. *
  33. Various regulatory agencies now recommend the use of ivabradine in patients with HR of 70 bpm or higher. *
  34. Oral anticoagulants are broadly utilized for long-term prevention and treatment of venous thromboembolism (VTE). *
  35. Dabigatran is a competitive direct thrombin inhibitor approved by the US FDA for prevention of embolic stroke in patients with nonvalvular atrial fibrillation. *
  36. Benefits of Dabigatran include- *
  37. Clinicians are rapidly prescribing this agent as a replacement for warfarin therapy *
  38. Dabigatran demonstrated a lower risk for intracranial bleeding, compared with warfarin. *
  39. What is considered an appropriate approach in your practice Reaching target dose or adding all molecules with proven mortality benefit? (based on symptoms and signs) *
  40. Which drugs among the present available one’s are preferred as first to be initiated in your practice and why? *