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Male Female
< 5 years
5-10 years
11-20 years
>20 years
Multi-specialty hospital
Clinic/ nursing home
Government hospital/ medical college
Mixed
Tier 1 city
Tier 2 city
Tier 3 city
Rural area
<10
11-20
21-30
31-40
If any other
Males
Females
Both
< 15 years
15-30 years
30-50 years
50 years and above
Very frequently
Frequently
Occasionally
Rarely
Generalized Anxiety Disorder Scale
Hamilton Anxiety Rating Scale (HAM-A)
Depression Anxiety Stress Scale
Clinical evaluation/experience
APA guidelines
NICE guidelines
IPS guidelines
Clinical practice guidelines (India)
Clinical experience
Etifoxine
Benzodiazepines
SSRI’ s & SNRI’s
Azapirone (Buspirone)
All the above (Depending on different conditions)
Respiratory depression
Sedation
Confusion
Amnesia
Visual disturbances
All the above
Side effects (Sedation, Amnesia, Confusion, Impaired coordination, Slurred speech etc.)
Dizziness
Dependency
Rebound anxiety/ Withdrawal symptoms
Suicidal ideation and behavior
Withdrawal symptoms
Sexual dysfunction
All of the above
Efficacy
Favorable safety profile
Once a day dosing
Patient acceptance
Yes
No
Sometimes
50 mg/ day
100 mg/ day
150 mg/day
200 mg/day
Direct potentiation of GABAA receptor by binding to β2/β3 subunits of the GABAA receptor
Modulation of GABAA receptors via stimulation of neurosteroid production.
1-2 days
3 - 5 days
1 weeks
2 weeks
Monotherapy
Add on therapy
<2 weeks
2 - 4 weeks
1-3 months
Depending on patients’ symptoms
No sedation
No psychomotor impairment
No dependence
No rebound anxiety
1 month
2-3 months
6 months
1 year or more
Hamilton anxiety rating scale
Clinical global impression (CGI-S, CGI-I, CGI-C)
Patient self-report
Other
Psychoeducation
Supportive therapy
Very effective
Moderately effective
Slightly effective
Not effective
Most tolerable and most effective
Equally tolerable and equally effective
Less tolerable but equally effective
Less tolerable and less effective